2,4'-dihydroxyacetophenone dioxygenase

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2,4'-dihydroxyacetophenone dioxygenase
Identifiers
EC number 1.13.11.41
CAS number 105503-64-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 2,4'-dihydroxyacetophenone dioxygenase (EC 1.13.11.41) is an enzyme that catalyzes the chemical reaction

2,4'-dihydroxyacetophenone + O2 4-hydroxybenzoate + formate

Thus, the two substrates of this enzyme are 2,4'-dihydroxyacetophenone and O2, whereas its two products are 4-hydroxybenzoate and formate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving). This enzyme is also called (4-hydroxybenzoyl)methanol oxygenase. This enzyme participates in bisphenol a degradation.[1]

References[edit]

  1. ^ Mayu Enya; Keiko Aoyagi; Yoshihiro Hishikawa; Azusa Yoshimura; Koichi Mitsukura; Kiyofumi Marayuma (2012). "Molecular and Catalytic Properties of 2,4′-Dihydroxyacetophenone Dioxygenase from Burkholderia sp. AZ11". Bioscience, Biotechnology, and Biochemistry. 76 (3): 567–574. doi:10.1271/bbb.110867.