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2S may refer to:

  • 2S, key signature of two sharps
  • a series of Toyota S engines
  • Birdman Chinook 2S, ultralight aircraft
  • 2s electron in an atomic orbital
  • 2szTV, a television channel in Senegal
  • 2S, a protein-folding intermediate with two disulphide bonds
  • Two-spirit, a term used by some indigenous North Americans to describe certain people in their communities who fulfill a traditional third-gender (or other gender-variant) ceremonial role in their cultures

See also[edit]