Allysine

From Wikipedia, the free encyclopedia
  (Redirected from 2-aminoadipate 6-semialdehyde)
Jump to: navigation, search
Allysine
Skeletal formula of zwitterion
Ball-and-stick model of the L-allysine molecule as a zwitteiron
Names
IUPAC name
2-amino-6-oxo-hexanoic acid
Other names
2-aminoadipate semialdehyde, 2-amino-5-formylvaleric acid, norvaline, 6-oxo-DL-norleucine
Identifiers
1962-83-0 N
3D model (Jmol) Interactive image
Interactive image
ChEBI CHEBI:57988 YesY
ChemSpider 202 YesY
KEGG C04076 YesY
MeSH allysine
PubChem 207
UNII 425I4Y24YZ YesY
Properties
C6H11NO3
Molar mass 145.16 g·mol−1
Density 1.74g/cm3
Boiling point 295.2 °C (563.4 °F; 568.3 K)
Hazards
Flash point 132.3 °C (270.1 °F; 405.4 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Allysine is a derivative of lysine, used in the production of elastin and collagen. It is produced by the actions of the enzyme lysyl oxidase in the extracellular matrix and is essential in the crosslink formation that stabilizes collagen and elastin.[1]

See also[edit]

References[edit]

  1. ^ Pinnell, SR; Martin, GR (October 1968). "The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone." (PDF). Proceedings of the National Academy of Sciences of the United States of America. 61 (2): 708–13, 716. doi:10.1073/pnas.61.2.708. PMC 225217Freely accessible. PMID 5246001.