2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase

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2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
Identifiers
EC number 5.2.1.10
CAS number 115629-29-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase (EC 5.2.1.10) is an enzyme that catalyzes the chemical reaction

cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide

Hence, this enzyme has one substrate, cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide, and one product, trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase. Other names in common use include 2-chlorocarboxymethylenebutenolide isomerase, and chlorodienelactone isomerase. This enzyme participates in 1,4-dichlorobenzene degradation.

References[edit]

  • Schwien U, Schmidt E, Knackmuss H-J and Reinecke W (1988). "Degradation of chlorosubstituted aromatic-compounds by Pseudomonas sp. strain-B13 - fate of 3,5-dichlorocatechol". Arch. Microbiol. 150: 78–84. doi:10.1007/BF00409721.