2-dehydro-3-deoxy-L-pentonate aldolase

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2-dehydro-3-deoxy-L-pentonate aldolase
Identifiers
EC number 4.1.2.18
CAS number 9076-49-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 2-dehydro-3-deoxy-L-pentonate aldolase (EC 4.1.2.18) is an enzyme that catalyzes the chemical reaction

2-dehydro-3-deoxy-L-pentonate pyruvate + glycolaldehyde

Hence, this enzyme has one substrate, 2-dehydro-3-deoxy-L-pentonate, and two products, pyruvate and glycolaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-L-pentonate aldolase, 2-keto-3-deoxy-L-arabonate aldolase, 2-keto-3-deoxy-D-xylonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.

References[edit]

  • Dahms AS, Anderson RL (1969). "2-keto-3-deoxyl-L-arabonate aldolase and its role in a new pathway of L-arabinose degradation". Biochem. Biophys. Res. Commun. 36 (5): 809–14. PMID 5808295. doi:10.1016/0006-291X(69)90681-0.