2-oxopent-4-enoate hydratase

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2-oxopent-4-enoate hydratase
Identifiers
EC number 4.2.1.80
CAS number 64427-80-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 2-oxopent-4-enoate hydratase (EC 4.2.1.80) is an enzyme that catalyzes the chemical reaction

4-hydroxy-2-oxopentanoate 2-oxopent-4-enoate + H2O

Hence, this enzyme has one substrate, 4-hydroxy-2-oxopentanoate, and two products, 2-oxopent-4-enoate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming). Other names in common use include 2-keto-4-pentenoate hydratase, OEH, 2-keto-4-pentenoate (vinylpyruvate)hydratase, and 4-hydroxy-2-oxopentanoate hydro-lyase. This enzyme participates in 9 metabolic pathways: phenylalanine metabolism, benzoate degradation via hydroxylation, biphenyl degradation, toluene and xylene degradation, 1,4-dichlorobenzene degradation, fluorene degradation, carbazole degradation, ethylbenzene degradation, and styrene degradation.

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