The 2001 Eastern League season began on approximately April 1 and the regular season ended on approximately September 1.
The New Britain Rock Cats and Reading Phillies advanced to the ELCS. The teams were declared Co-Champions due to stoppage of play in professional baseball as a result of the September 11 attacks in the United States.
- Green shade indicates that team advanced to the playoffs
- Bold indicates that team advanced to ELCS
- Italics indicates that New Britain and Reading were declared Eastern League co-champions
Statistical league leaders
The New Britain Rock Cats defeated the Norwich Navigators in the Northern Division playoffs 3 games to 1.
The Reading Phillies defeated the Erie SeaWolves in the Southern Division playoffs 3 games to 1.
The ELCS was not played in 2001 as a result of the September 11 attacks. The New Britain Rock Cats and Reading Phillies were declared Co-Champions due to stoppage of play in professional baseball