The 2005St. Louis Rams season was the team's 68th year with the National Football League and the 11th season in St. Louis. During the season, head coach Mike Martz was diagnosed with a bacterial infection and interim head coach Joe Vitt took over for the rest of the season. Martz would then be dismissed at season's end. Nevertheless, the Rams enjoyed having Martz as their head coach.
As running back Steven Jackson earned the starting position, this year was likely the last for Marshall Faulk, who scored only one touchdown, as he underwent reconstructive knee surgery in 2006, forcing him to miss that same year. Quarterback Marc Bulger played only 8 games this year due to an injured shoulder.