The year 2006 in architecture involved some significant architectural events and new buildings.
Eureka Tower, Southbank, Melbourne
- February 5 - Madrid-Barajas Airport Terminal 4 inaugurated, designed by Antonio Lamela and Richard Rogers.
- March 1 - The Senedd, the National Assembly building in Cardiff, Wales, by architect Richard Rogers, is opened by Queen Elizabeth II of the United Kingdom.
- April 4 - Busch Stadium, designed by Populous (formerly HOK sport), opened as the new home of the St. Louis Cardinals.
- May 4 - Hearst Tower employees move into the Norman Foster designed, diagrid building near Columbus Circle, in New York City.
- May 5 - Aurora Tower opened to the public as the tallest building in Brisbane, Australia.
- May 19 - Mercedes-Benz Museum, Stuttgart, Germany, designed by UNStudio, opened.
- May 23 - 7 World Trade Center officially opened the new building designed by Skidmore, Owings & Merrill at noon, with a free concert.
- May 26 - Berlin Hauptbahnhof (Berlin Main Station) opening ceremony. Design from the winning competition entry by the Hamburg architecture firm Gerkan, Marg and Partners.
- June 14 - Four Seasons Centre for the Performing Arts grand opening in Toronto, Ontario, Canada, by Canadian Diamond and Schmitt Architects.
- June 16 - The National Library of Belarus opened in Minsk, Belarus in the shape of a rhombicuboctahedron.
- June 26 - Savill Building opens at the Savill Garden in Windsor Great Park, Surrey, with a gridshell roof designed by Glen Howells Architects.
- July 22 - Emirates Stadium, designed by Populous, opened in the London Borough of Islington for the Arsenal Football Club.
- Summer - House of Sweden (the Swedish embassy) completed in Washington, D.C., designed by Swedish architects Gert Wingårdh and Tomas Hansen.
- September - Museum of Modern Literature (Literaturmuseum der Moderne or LiMo) opened in Marbach, Germany, by British architect David Chipperfield.
- September 2 - Bishan Community Library opened in Singapore.
- October - Janelia Farm Research Campus completed in Loudoun County, Virginia, by Rafael Viñoly.
- October 5 - The Arsht Center opens in Downtown Miami, Florida as the third largest performing arts center in the United States.
- October 11 - Eureka Tower a 297.3 metres (975 ft) residential skyscraper, designed by Fender Katsalidis Architects, opens in Melbourne, Australia.
- October 26 - Klaus Advanced Computing Building officially opened on the campus of Georgia Institute of Technology, by American architects Perkins+Will.
- October 27 - Vesteda Tower a 90 m (300 ft) residential tower, designed by Jo Coenen, opens in Eindhoven, Netherlands.
- November - Maggie's Centre, Kirkcaldy, Scotland, a drop-in cancer care centre; Zaha Hadid's first built work in the United Kingdom.
- December 1
- date unknown - America's Cup Building inaugurated in Valencia, Spain, designed by British architect David Chipperfield.
- date unknown
- Accordia housing development in Cambridge, UK, phase 1 construction, designed by Feilden Clegg Bradley Studios with Maccreanor Lavington and Alison Brooks Architects (Stirling Prize 2008).
- Saint-Pierre, Firminy, France, completed by José Oubrerie to a church design by Le Corbusier (died 1965) begun in 1971.
- CNOOC Building in Beijing, designed by American architects Kohn Pedersen Fox.
- KUMU (KUnstiMUuseum), Tallinn, Estonia, designed by Finnish architect Pekka Vapaavuori.