The 2008 Toledo Rockets football team represented the University of Toledo during the 2008 NCAA Division I FBS football season. Toledo competed as a member of the West Division of the Mid-American Conference (MAC). The Rockets were led by Tom Amstutz in his eighth and final year as head coach.
Toledo finished the year 3–9 overall and 2–6 in conference play. The season highlight was a 13–10 victory over the Michigan Wolverines; Michigan entered the game 24–0 against MAC teams.
|September 6||10:00 PM||at Arizona*||L 16–41||50,939|
|September 13||12:00 PM||at Eastern Michigan||W 41–17||16,860|
|September 20||8:15 PM||No. 25 Fresno State*||ESPNU||L 54–55 2OT||20,096|
|September 27||7:00 PM||Florida International*||L 16–35||19,004|
|October 4||7:00 PM||Ball State||L 0–31||18,009|
|October 11||12:00 PM||at Michigan*||BTN||W 13–10||107,267|
|October 18||4:00 PM||at Northern Illinois||L 7–38||22,092|
|October 25||12:00 PM||at Central Michigan||ESPN+||L 23–24||21,422|
|November 5||7:00 PM||at Akron||ESPNU||L 30–47||10,134|
|November 15||2:00 PM||at Western Michigan||FS Detroit||L 17–27||12,336|
|November 21||7:00 PM||Miami (OH)||W 42–14||12,251|
|November 28||3:30 PM||Bowling Green||ESPN Classic||L 10–38||11,264|