11 to 11 July – The 2010 FIFA World Cup takes place in South Africa and is won by Spain, with the Netherlands as the runner-up.
2 – Former Chief of Police and Chief of Interpol, Jackie Selebi, is found guilty of corruption, but not guilty on further charges of perverting the course of justice.
25 – In the Blackheath train accident a minibus carrying 14 school children is struck by a train at a level crossing in Cape town. Nine die on the scene and a 10th child later dies in hospital.
24-26 – President Jacob Zuma leads a delegation of over 200 South African business leaders and entrepreneurs to the People's Republic of China to promote trade and investment between the two countries.
13 – Anni Dewani, while on her honeymoon in South Africa, is kidnapped and then murdered in Gugulethu township near Cape Town.