This was the first season with a single-league format for each region, which replaced the group format used until the previous season. A total of 12 national associations were represented in the league stage.
Gwangju FC made their debut appearances in the Champions League since the introduction of the group stage. This also marked Gwangju's debut appearances in Asian football. Gwangju's Jasir Asani was the first-ever goalscorer of the competition's league stage.
For each region, the title holder or the highest seeded team from each member association involved were allocated into Pot 1, while the remaining teams were allocated into Pot 2.[3]
Each team was drawn a position in the draw grid for their region: column A–C for West and D–F for East. Teams from Pot 1 were drawn into positions 1 or 2 while teams from Pot 2 were drawn into positions 3 or 4.
Each position had pre-determined matchups as part of a pairings grid. Teams in each column played matches with the other columns in each region.[3]
Source: Asian Football Confederation Rules for classification: 1) points; 2) goal difference; 3) number of goals scored; 4) number of matches won; 5) penalty shoot-out if only two teams remain tied and played each other on the final matchday 6) fair play ranking; 7) drawing of lots
Source: Asian Football Confederation Rules for classification: 1) points; 2) goal difference; 3) number of goals scored; 4) number of matches won; 5) penalty shoot-out if only two teams remain tied and played each other on the final matchday 6) fair play ranking; 7) drawing of lots Notes:
^Shandong Taishan were considered to have withdrawn from the AFC Champions League Elite after the club confirmed that it did not intend to report for their league stage match against Ulsan HD on 19 February 2025.[8] Their remaining fixture was cancelled, with their seven played matches being expunged.[9]