|Millennium:||1st millennium BC|
|Centuries:||4th century BC – 3rd century BC – 2nd century BC|
|Decades:||240s BC 230s BC 220s BC – 210s BC – 200s BC 190s BC 180s BC|
|Years:||219 BC 218 BC 217 BC – 216 BC – 215 BC 214 BC 213 BC|
|216 BC by topic|
|Gregorian calendar||216 BC|
|Ab urbe condita||538|
|Ancient Egypt era||XXXIII dynasty, 108|
|- Pharaoh||Ptolemy IV Philopator, 6|
|Ancient Greek era||141st Olympiad (victor)¹|
|Chinese calendar||甲申年 (Wood Monkey)
2481 or 2421
— to —
乙酉年 (Wood Rooster)
2482 or 2422
|Coptic calendar||−499 – −498|
|Ethiopian calendar||−223 – −222|
|- Vikram Samvat||−159 – −158|
|- Shaka Samvat||N/A|
|- Kali Yuga||2886–2887|
|Iranian calendar||837 BP – 836 BP|
|Islamic calendar||863 BH – 862 BH|
|Minguo calendar||2127 before ROC
|Seleucid era||96/97 AG|
|Thai solar calendar||327–328|
|Wikimedia Commons has media related to 216 BC.|
Year 216 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Varro and Paullus (or, less frequently, year 538 Ab urbe condita). The denomination 216 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- The Carthaginian general, Hannibal, moves his forces southward through Italy and seizes the large army supply depot at Cannae on the Aufidus River.
- August 2 – The Battle of Cannae (east of Naples) ends in victory for Hannibal whose 40,000-man army defeats a Roman force of 70,000 led by consuls Lucius Aemilius Paullus (who is killed in the battle) and Gaius Terentius Varro.
- A loan of money and supplies for the Roman army in Sicily is sought and obtained from Hiero II of Syracuse.
- The Roman historian Quintus Fabius Pictor is sent to Delphi in Greece to consult the Oracle for advice about what Rome should do after its defeat in the Battle of Cannae.
- Following Hannibal's victory, many regions begin to defect from Rome, while others are conquered by Hannibal's forces. In Apulia, Lucania, Samnium and in Bruttium, Hannibal finds many supporters.
- The city of Capua switches sides to join Hannibal and the Carthaginian army winters there.
- After the defeat at Cannae, Roman general, Marcus Claudius Marcellus, commands the remnants of the Roman army at Canusium and saves the city of Nola and southern Campania from occupation by Hannibal.
- A Roman force of 25,000 led by Lucius Postumius Albinus is ambushed by Gauls near Litana and almost completely wiped out.
- Hasdrubal is ordered by the Carthaginian government to march to Italy.
- Roman forces in Spain led by Gnaeus Cornelius Scipio Calvus and Publius Cornelius Scipio successfully thwart Hasdrubal's attempt to march to Italy.
- Philip V of Macedon, still resenting Rome's interference in Illyrian politics, seizes his opportunity to invade Illyria. Ambassadors from Philip V visit Hannibal at his headquarters in Italy. These actions mark the beginning of the First Macedonian War between Rome and Macedonia.
- A revolt of the Egyptian peasants is put down by Ptolemy IV.
- August 2
- After August 2 – Gelo, son of Hiero II
- Polybius, The Histories, 3:107.2–3
- Livy, Ab Urbe Condita, 22.44–51
- Livy, Ab Urbe Condita, 23.21
- Livy, Ab Urbe Condita, 22.57
- Livy, Ab Urbe Condita, 22.61
- Livy, Ab Urbe Condita, 23.24
- Livy, Ab Urbe Condita, 23.27
- Livy, Ab Urbe Condita, 23.29
- Livy, Ab Urbe Condita, 22.56
- Livy, Ab Urbe Condita, 22.49
- Livy, Ab Urbe Condita, 23.30