Year 226 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Messalla and Fullo (or, less frequently, year 528 Ab urbe condita). The denomination 226 BC for this year has been used since the early medieval period, when the Anno Dominicalendar era became the prevalent method in Europe for naming years.
The Romans send an embassy to Hasdrubal and conclude a treaty which prohibits him from waging war north of the river Ebro, but allowing him a free hand to the south even at the expense of the interests of the town of Massilia.
Seleucus II dies after a fall from his horse and is succeeded by his eldest son Seleucus III Soter. At the time of Seleucus II's death, the empire of the Seleucids, with its capital at Antioch on the Orontes, stretches from the Aegean Sea to the borders of India and includes southern Anatolia, Mesopotamia, Persia, and northern Syria. Dynastic power is upheld by a mercenaryarmy and by the loyalty of many Greek cities founded by Alexander the Great and his successors. The strength of the empire is already being sapped by repeated revolts in its eastern provinces and dissention amongst the members of the Seleucid dynasty.