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23S rRNA (uracil747-C5)-methyltransferase

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23S rRNA (uracil747-C5)-methyltransferase
Identifiers
EC no.2.1.1.189
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

23S rRNA (uracil747-C5)-methyltransferase (EC 2.1.1.189, YbjF, RumB, RNA uridine methyltransferase B) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uracil747-C5)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uracil747 in 23S rRNA S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA

The enzyme specifically methylates uracil747 at C5 in 23S rRNA.

References

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  1. ^ Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S (August 2003). "Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry". Nucleic Acids Research. 31 (16): 4738–46. doi:10.1093/nar/gkg657. PMC 169892. PMID 12907714.
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