28S ribosomal RNA

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16S and 28S phylogenies of three Waldo species

28S ribosomal RNA is the structural RNA for the large component, or large subunit (LSU) of eukaryotic cytoplasmic ribosomes, and thus one of the basic components of all eukaryotic cells.[1] It is the eukaryotic nuclear homologue of the prokaryotic 23S ribosomal RNA.

The genes coding for 28S rRNA are referred to as 28S rDNA. The Sequences from these genes are sometimes used in molecular analysis to construct phylogenetic trees.[2]


  1. ^ Lodish, H. (1995). Molecular Cell Biology, 3rd ed. Freeman.
  2. ^ Mallatt, Jon; Sullivan, Jack (December 1998). "28S and 18S rDNA sequences support the monophyly of lampreys and hagfishes". Molecular Biology and Evolution. 15 (12): 1706–18. doi:10.1093/oxfordjournals.molbev.a025897. PMID 9866205.