|Millennium:||1st millennium BC|
|295 BC by topic|
|Gregorian calendar||295 BC|
|Ab urbe condita||459|
|Ancient Egypt era||XXXIII dynasty, 29|
|- Pharaoh||Ptolemy I Soter, 29|
|Ancient Greek era||121st Olympiad, year 2|
|Balinese saka calendar||N/A|
|Chinese calendar||乙丑年 (Wood Ox)|
2402 or 2342
— to —
丙寅年 (Fire Tiger)
2403 or 2343
|Coptic calendar||−578 – −577|
|Ethiopian calendar||−302 – −301|
|- Vikram Samvat||−238 – −237|
|- Shaka Samvat||N/A|
|- Kali Yuga||2806–2807|
|Iranian calendar||916 BP – 915 BP|
|Islamic calendar||944 BH – 943 BH|
|Minguo calendar||2206 before ROC|
|Seleucid era||17/18 AG|
|Thai solar calendar||248–249|
−168 or −549 or −1321
— to —
−167 or −548 or −1320
Year 295 BC was a year of the pre-Julian Roman calendar. It was known at the time as the Year of the Consulship of Rullianus and Mus (or, less frequently, year 459 Ab urbe condita). The denomination 295 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- The Battle of Sentinum west of Anconum ends in defeat for a formidable coalition of Samnites, Etruscans, Umbri, and their Gallic allies at the hands of the Roman legions commanded by consuls Publius Decius Mus (who is killed in the battle) and Quintus Fabius Maximus Rullianus. The Romans lose nearly 8,000 men but kill some 25,000 men of the enemy and force peace on the Etruscans.
- August 19 – The first temple to Venus, the Roman goddess of love, beauty and fertility, is dedicated by Quintus Fabius Maximus Gurges during the Third Samnite War.
- Athens falls to Demetrius Poliorcetes after a bitter siege, and its tyrant Lachares is killed.
- The king of Macedon, Antipater II, murders his mother Thessalonike, accusing her of being too fond of his brother and co-ruler Alexander V.
- Apollonius of Rhodes, Greek poet and librarian (approximate date)
- Ptolemy, son of Pyrrhus of Epirus (d. 272 BC)
- Egnatius, Roman military leader of the Samnites
- Publius Decius Mus, Roman consul (killed in the Battle of Sentinum)
- Thessalonike of Macedon, daughter of king Philip II of Macedon and wife of Cassander (b. 352 BC)
- Wuling of Zhao, Chinese king of Zhao (b. 340 BC)
- Zhuang Zhou, Chinese philosopher (approximate date)