2H or 2-H may refer to:
- Deuterium, or 2H, an isotope of Hydrogen
- 2nd half of a fiscal year
- 2H lead, a type of lead in a pencil
- 2H, a type of Toyota H engine
- 2H, a type of Volkswagen EA827 engine
- Douglas O-2H, a model of Douglas O-2
- Chaparral 2H, one model of Chaparral Cars
- Aptera 2h, a model in the Aptera 2 Series
- SSH 2H (WA), alternate designation for Washington State Route 290
- 2H, a disgnation for chemicals with two hydrogen molecules
- 2H-pyran, a form of Pyran
- 2H-1-benzopyran, a form of Benzopyran
- 2H-pyran-2-one, a form of 2-Pyrone
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