2Q or 2-Q may refer to:
- The second quarter of a calendar year (April, May, June) or fiscal year
- 2Q, IATA code for Air Cargo Carriers
- F3D-2Q, a model of Douglas F3D Skyknight
- WV-2Q, a model of Lockheed EC-121 Warning Star
- 2q, an arm of Chromosome 2 (human)
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