3,3'-Diindolylmethane

3,3'-Diindolylmethane
Names
	Preferred IUPAC name 3,3′-Methylenedi(1H-indole)
	Other names 3-(1H-Indol-3-ylmethyl)-1H-indole; 3,3′-Methylenebis-1H-indole; DIM
Identifiers
CAS Number	1968-05-4 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	223072
ChEBI	CHEBI:50182 ;
ChEMBL	ChEMBL446452 ;
ChemSpider	2963 ;
DrugBank	DB11875;
ECHA InfoCard	100.124.716
EC Number	606-355-3;
IUPHAR/BPS	11208;
PubChem CID	3071;
UNII	SSZ9HQT61Z ;
CompTox Dashboard (EPA)	DTXSID8037047 ;
	InChI InChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2 Key: VFTRKSBEFQDZKX-UHFFFAOYSA-N ; InChI=1/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2; InChI=1/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2 Key: VFTRKSBEFQDZKX-UHFFFAOYAU;
	SMILES c4ccc3c(Cc1c[nH]c2ccccc12)c[nH]c3c4;
Properties
Chemical formula	C17H14N2
Molar mass	246.313 g·mol−1
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335, H413
Precautionary statements	P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

3,3′-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables, such as broccoli, Brussels sprouts, cabbage and kale.^[1] It and its parent compound – indole-3-carbinol – are under laboratory research to determine their possible biological properties, particularly in anti-cancer mechanisms.^[1]^[2]^[3] DIM is sold as a dietary supplement.^[1]

Properties[edit]

^ ^a ^b ^c ^d ^e "Indole-3-carbinol". Micronutrient Information Center, Linus Pauling Institute, Oregon State University. 1 July 2017. Retrieved 11 July 2022.
^ ^a ^b "Indole-3-Carbinol". Memorial Sloan Kettering Cancer Center. Retrieved 2019-09-03.
^ ^a ^b "3,3'-Diindolylmethane". PubChem, US National Library of Medicine. 9 July 2022. Retrieved 11 July 2022.
^ Rajendran, P; Ho, E; Williams, DE; Dashwood, RH (2011). "Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells". Clin Epigenetics. 3 (1): 4. doi:10.1186/1868-7083-3-4. PMC 3255482. PMID 22247744.