3,4-Dihydroxymandelic acid

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3,4-Dihydroxymandelic acid
3,4-Dihydroxymandelic acid.svg
IUPAC name
2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid
775-01-9 N
ChEBI CHEBI:27637 YesY
ChemSpider 77371 YesY
Jmol 3D model Interactive image
KEGG C05580 YesY
MeSH 3,4-dihydroxymandelic+acid
PubChem 85782
Molar mass 184.14612
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

3,4-Dihydroxymandelic acid (DHMA, DOMA) is a metabolite of norepinephrine.[1]

Norepinephrine degradation. 3,4-Dihydroxymandelic acid is shown at right. Enzymes are shown in boxes.[2]


  1. ^ Ley JP; Engelhart K; Bernhardt J; Bertram HJ (October 2002). "3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential". J. Agric. Food Chem. 50 (21): 5897–902. doi:10.1021/jf025667e. PMID 12358456. 
  2. ^ Figure 11-4 in: Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.