3,4-Dihydroxystyrene

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3,4-Dihydroxystyrene
3,4-Dihydroxystyrene.png
3,4-dihydroxystyrene-3D-balls.png
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
Formula C8H8O2
Molar mass 136.15 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.

See also[edit]

References[edit]

  1. ^ Koizumi S; Matsushima Y; Nagatsu T; Iinuma H; Takeuchi T; Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica et Biophysica Acta. 789 (2): 111–8. doi:10.1016/0167-4838(84)90194-8. PMID 6148105.