3-Maleylpyruvic acid

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3-Maleylpyruvic acid
3-Maleylpyruvic acid.svg
Names
IUPAC name
(Z)-4,6-Dioxohept-2-enedioic acid
Identifiers
ChEBI CHEBI:30859
ChemSpider 4444134
Jmol 3D model Interactive image
PubChem 5280494
6857405 (dianion)
Properties
C7H6O6
Molar mass 186.12 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

3-Maleylpyruvic acid, or 3-maleylpyruvate, is a dicarboxylic acid formed by the oxidative ring opening of gentisic acid by gentisate 1,2-dioxygenase during the metabolism of tyrosine.[1] It is converted into 3-fumarylpyruvate by maleylpyruvate isomerase.[2]

References[edit]

  1. ^ Sugiyama S, Yano K, Komagata K, Arima K (1960). "Metabolites of aromatic compounds by microbes. Part VII. Gentisic acid oxidase". Bull. Agric. Chem. Soc. Jpn. 24: 243–248. 
  2. ^ Lack L (1961). "Enzymic cis-trans isomerization of maleylpyruvic acid". J. Biol. Chem. 236: 2835–2840. PMID 14461395.