3-Nitrobenzanthrone

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3-Nitrobenzanthrone
3-Nitrobenzanthrone.png
Names
IUPAC name
3-Nitro-3,3a-dihydro-benzo[de]anthracen-7-one
Identifiers
3D model (JSmol)
ChemSpider
Properties
C17H9NO3
Molar mass 275.26 g/mol
Melting point 248 °C (478 °F; 521 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

3-Nitrobenzanthrone (3-nitro-7H-benz[de]anthracen-7-one) is a chemical compound emitted in diesel exhaust; it is a potent carcinogen.[2] It produced the highest score ever reported in the Ames test, a standard measure of the cancer-causing potential of toxic chemicals, far greater than the previous known strongest (1,8-dinitropyrene, which is also found in diesel exhaust).[3]

See also[edit]

References[edit]

  1. ^ Hansen, Tanja; Seidel, Albrecht; Borlak, Juergen (2007). "The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells". Toxicology and Applied Pharmacology. 221 (2): 222–234. PMID 17477947. doi:10.1016/j.taap.2007.03.003. 
  2. ^ Volker M. Arlt (2005). "3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence". Mutagenesis. 20 (6): 399–410. PMID 16199526. doi:10.1093/mutage/gei057. 
  3. ^ Fred Pearce (Oct 25, 1997). "Devil in the diesel". New Scientist: 4.