3-oxoadipate enol-lactonase

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3-oxoadipate enol-lactonase
Identifiers
EC number3.1.1.24
CAS number9031-04-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a 3-oxoadipate enol-lactonase (EC 3.1.1.24) is an enzyme that catalyzes the chemical reaction

3-oxoadipate enol-lactone + H2O 3-oxoadipate

Thus, the two substrates of this enzyme are 3-oxoadipate enol-lactone and H2O, whereas its product is 3-oxoadipate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase. Other names in common use include carboxymethylbutenolide lactonase, beta-ketoadipic enol-lactone hydrolase, 3-ketoadipate enol-lactonase, 3-oxoadipic enol-lactone hydrolase, and beta-ketoadipate enol-lactone hydrolase. This enzyme participates in benzoate degradation via hydroxylation.

References[edit]

  • Ornston LN (August 1966). "The conversion of catechol and protocatechuate to beta-ketoadipate by Pseudomonas putida. II. Enzymes of the protocatechuate pathway". The Journal of Biological Chemistry. 241 (16): 3787–94. PMID 5916392.
  • Ornston LN (1970). "Conversion of catechol and protocatechuate to beta-ketoadipate (Pseudomonas putida)". Methods Enzymol. 17A: 529–549. doi:10.1016/0076-6879(71)17237-0.