4,5-dihydroxyphthalate decarboxylase

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4,5-dihydroxyphthalate decarboxylase
Identifiers
EC number 4.1.1.55
CAS number 37290-48-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 4,5-dihydroxyphthalate decarboxylase (EC 4.1.1.55) is an enzyme that catalyzes the chemical reaction

4,5-dihydroxyphthalate 3,4-dihydroxybenzoate + CO2

Hence, this enzyme has one substrate, 4,5-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming). This enzyme is also called 4,5-dihydroxyphthalate carboxy-lyase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References[edit]

  • Ribbons DW; Evans WC (1966). "Oxidative metabolism of phthalic acid by soil pseudomonads". Biochem. J. 76: 310–318.