5-Formyluracil

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5-Formyluracil
5-Formyluracil.svg
Names
IUPAC name
2,4-Dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.153.693
KEGG
UNII
Properties
C5H4N2O3
Molar mass 140.098 g·mol−1
Hazards
GHS pictograms The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word Warning
H315, H319, H335
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

5-Formyluracil is a heterocyclic organic base. It is produced from the oxidation of the methyl group of thymine. It is mutagenic.[1]

References[edit]

  1. ^ Klungland, A; Paulsen, R; Rolseth, V; Yamada, Y; Ueno, Y; Wiik, P; Matsuda, A; Seeberg, E; Bjelland, S. "5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism". Toxicol Lett. 119: 71–8. doi:10.1016/s0378-4274(00)00308-8. PMID 11275423.