5-Methoxysalicylic acid

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5-Methoxysalicylic acid
5-Methoxysalicylic acid.png
IUPAC name
2-hydroxy-5-methoxybenzoic acid
Other names
2-Hydroxy-5-methoxybenzoic acid
6-Hydroxy-m-anisic acid
5-Methoxy-2-hydroxybenzoic acid
m-Anisic acid
ChemSpider 68296
Jmol-3D images Image
PubChem 75787
Molar mass 168.14 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

5-Methoxysalicylic acid is a chemical compound. It is a component of castoreum, the exudate from the castor sacs of the mature beaver.[1]

A mixture of 5-methoxysalicylic acid and spermine can be used as a matrix for oligonucleotides analysis in MALDI mass spectrometry.[2]

It is an isomer of vanillic acid.


  1. ^ Müller-Schwarze, D.; Houlihan, Peter W. (1991). "Pheromonal activity of single castoreum constituents in beaver,Castor canadensis". Journal of Chemical Ecology 17 (4): 715–734. doi:10.1007/BF00994195. PMID 24258917. 
  2. ^ Distler, AM; Allison, J (2001). "5-Methoxysalicylic acid and spermine: A new matrix for the matrix-assisted laser desorption/ionization mass spectrometry analysis of oligonucleotides". Journal of the American Society for Mass Spectrometry 12 (4): 456–62. doi:10.1016/S1044-0305(01)00212-4. PMID 11322192.