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53 may refer to:
- 53 (number)
- one of the years 53 BC, AD 53, 1953, 2053
- FiftyThree, an American privately held technology company that specializes in tools for mobile creation and visual thinking
- 53rd Regiment Alabama Cavalry
- 53rd Regiment of Foot (disambiguation)
- 53rd Division (disambiguation)
| disambiguation page lists articles associated with the same number.
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