The 6th century is the period from 501 to 600 in accordance with the Julian calendar in the Common Era. In the West this century marks the end of Classical Antiquity and the beginning of the Middle Ages. Following the collapse of the Western Roman Empire late in the previous century, Europe fractured into many small Germanic Kingdoms, which competed fiercely for land and wealth. From this upheaval the Franks rose to prominence, and carved out a sizeable domain encompassing much of modern France and Germany. Meanwhile, the surviving Eastern Roman Empire began to expand under the emperor Justinian, who eventually recaptured North Africa from the Vandals, and attempted to fully recover Italy as well in the hope of re-establishing Roman control over the lands once ruled by the Western Roman Empire.
Early 6th century – Archangel Michael, panel of a dyptich probably from the court workshop at Constantinople, is made. It is now kept at The British Museum, London.
Early 6th century – Irish colonists and invaders, the Scots, began migrating to Caledonia (later known as Scotland). Migration from south-west Britain to Brittany.
Early 6th century - Cassiodorus founds a cenobitic monastery and scrinium at Vivarium in Italy
502: Chinese annals mentioned the existence of the Buddhist Kingdom, Kanto Lim in South Sumatra, presumably in the neighborhood of present-day Palembang.
In 589 AD, the Chinese scholar-official Yan Zhitui makes the first reference to the use of toilet paper in history.
Significant to the history of agriculture, the Chinese author Jia Sixia wrote the treatise Qi Min Yao Shu in 535, and although it quotes 160 previous Chinese agronomy books, it is the oldest existent Chinese agriculture treatise. In over one hundred thousand written Chinese characters, the book covered land preparation, seeding, cultivation, orchard management, forestry, animal husbandry, trade, and culinary uses for crops.