ESCO1

ESCO1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MXE
Identifiers
Aliases	ESCO1, A930014I12Rik, CTF, ECO1, EFO1, ESO1, establishment of sister chromatid cohesion N-acetyltransferase 1
External IDs	OMIM: 609674; MGI: 1925055; HomoloGene: 62166; GeneCards: ESCO1; OMA:ESCO1 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	21,600,884 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	10,610,352 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; pancreatic epithelial cell; ; tibialis anterior muscle; ; secondary oocyte; ; Achilles tendon; ; deltoid muscle; ; testicle; ; gonad; ; epithelium of nasopharynx;
	Top expressed in
	saccule; ; zygote; ; primary oocyte; ; secondary oocyte; ; otic placode; ; otic vesicle; ; mesenteric lymph nodes; ; lacrimal gland; ; cumulus cell; ; olfactory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; metal ion binding; N-acetyltransferase activity; zinc ion binding; peptide-lysine-N-acetyltransferase activity; identical protein binding; acetyltransferase activity;
Cellular component	chromatin; nucleus; nucleoplasm; chromosome;
Biological process	post-translational protein acetylation; cell cycle; sister chromatid cohesion; regulation of DNA replication; peptidyl-lysine acetylation;
	Sources:Amigo / QuickGO
Orthologs
	114799
	77805
	ENSG00000141446
	ENSMUSG00000024293
	Q5FWF5
	Q69Z69
	NM_052911
	NM_001081222; NM_144542
	NP_443143
	NP_001074691
	Wikidata
View/Edit Human	View/Edit Mouse

Establishment of sister chromatid cohesion N-acetyltransferase 1 is a protein that in humans is encoded by the ESCO1 gene.^[5]

Function

ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141446 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024293 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Establishment of sister chromatid cohesion N-acetyltransferase 1". Retrieved 2015-09-17.
^ Hou F, Zou H (2005). "Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion". Molecular Biology of the Cell. 16 (8): 3908–18. doi:10.1091/mbc.E04-12-1063. PMC 1182326. PMID 15958495.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human N-acetyltransferase ESCO1

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000141446 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024293 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Establishment of sister chromatid cohesion N-acetyltransferase 1". Retrieved 2015-09-17.

[pmid15958495-6] Hou F, Zou H (2005). "Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion". Molecular Biology of the Cell. 16 (8): 3908–18. doi:10.1091/mbc.E04-12-1063. PMC 1182326. PMID 15958495.

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