A-41988

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A-41988
A-41988.png
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC28H32FNO2
Molar mass433.567 g·mol−1
3D model (JSmol)
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A-41988 (BW29Y) is an analgesic drug which acts as a cannabinoid agonist. It was developed by Abbott Laboratories in the 1970s,[1][2] and researched for potential use in the treatment of glaucoma,[3] but never commercialised.

See also[edit]

References[edit]

  1. ^ Winn M, Arendsen D, Dodge P, Dren A, Dunnigan D, Hallas R, et al. (April 1976). "Drugs derived from cannabinoids. 5. delta6a,10a-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains". Journal of Medicinal Chemistry. 19 (4): 461–71. doi:10.1021/jm00226a003. PMID 817021.
  2. ^ Guterman A, Somani P, Bachand RT (1979). "Phase-I evaluation of 5-5-dimethyl-10-hydroxy-8-[5-(4-fluorophenyl)-2-pentyl]-2-(2-propynyl-1, 2, 3, 4-tetrahydro-5h-[1] benzopyrano [3, 4-d] pyridine (a-41988)-novel benzopyran derivative". Clinical Pharmacology and Therapeutics. 25: 227.
  3. ^ Tiedeman JS, Shields MB, Weber PA, Crow JW, Cocchetto DM, Harris WA, Howes JF (March 1981). "Effect of synthetic cannabinoids on elevated intraocular pressure". Ophthalmology. 88 (3): 270–7. doi:10.1016/s0161-6420(81)35052-0. PMID 7015221.