From Wikipedia, the free encyclopedia
Jump to: navigation, search
ATP-binding cassette, sub-family B (MDR/TAP), member 9
Symbols ABCB9 ; EST122234; TAPL
External IDs OMIM605453 MGI1861729 HomoloGene10491 ChEMBL: 1293189 GeneCards: ABCB9 Gene
RNA expression pattern
PBB GE ABCB9 214209 s at tn.png
PBB GE ABCB9 207321 s at tn.png
More reference expression data
Species Human Mouse
Entrez 23457 56325
Ensembl ENSG00000150967 ENSMUSG00000029408
UniProt Q9NP78 Q9JJ59
RefSeq (mRNA) NM_001243013 NM_019875
RefSeq (protein) NP_001229942 NP_063928
Location (UCSC) Chr 12:
122.92 – 122.98 Mb
Chr 5:
124.06 – 124.1 Mb
PubMed search [1] [2]

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.[1][2]

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.[2]

See also[edit]


  1. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum Mol Genet 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702. 
  2. ^ a b "Entrez Gene: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.