ABCB9

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ABCB9
Identifiers
Aliases ABCB9, EST122234, TAPL, ATP binding cassette subfamily B member 9
External IDs MGI: 1861729 HomoloGene: 10491 GeneCards: 23457
RNA expression pattern
PBB GE ABCB9 207321 s at tn.png

PBB GE ABCB9 214209 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019875

RefSeq (protein)

NP_001229942.1
NP_001229943.1
NP_062570.1
NP_062571.1
NP_982269.2

NP_063928.2

Location (UCSC) Chr 12: 122.92 – 122.98 Mb Chr 5: 124.06 – 124.1 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.[1][2]

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.[2]

See also[edit]

References[edit]

  1. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum Mol Genet 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702. 
  2. ^ a b "Entrez Gene: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.