ABCB9

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ABCB9
Identifiers
Aliases ABCB9, EST122234, TAPL, ATP binding cassette subfamily B member 9
External IDs MGI: 1861729 HomoloGene: 10491 GeneCards: ABCB9
Gene location (Human)
Chromosome 12 (human)
Chr. Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for ABCB9
Genomic location for ABCB9
Band 12q24.31 Start 122,920,951 bp[1]
End 122,981,649 bp[1]
RNA expression pattern
PBB GE ABCB9 207321 s at fs.png

PBB GE ABCB9 214209 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019875

RefSeq (protein)

NP_001229942
NP_001229943
NP_062570
NP_062571
NP_982269

NP_063928

Location (UCSC) Chr 12: 122.92 – 122.98 Mb Chr 12: 124.06 – 124.1 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.[5][6]

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000150967 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029408 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database". Hum Mol Genet. 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702. 
  6. ^ a b "Entrez Gene: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.