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ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Symbols ABCC10 ; EST182763; MRP7; SIMRP7
External IDs OMIM612509 MGI2386976 HomoloGene58616 GeneCards: ABCC10 Gene
RNA expression pattern
PBB GE ABCC10 213485 s at tn.png
PBB GE ABCC10 215873 x at tn.png
More reference expression data
Species Human Mouse
Entrez 89845 224814
Ensembl ENSG00000124574 ENSMUSG00000032842
UniProt Q5T3U5 Q8R4P9
RefSeq (mRNA) NM_001198934 NM_145140
RefSeq (protein) NP_001185863 NP_660122
Location (UCSC) Chr 6:
43.43 – 43.45 Mb
Chr 17:
46.3 – 46.33 Mb
PubMed search [1] [2]

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.[1][2]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.[2]

See also[edit]


  1. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum Mol Genet 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702. 
  2. ^ a b "Entrez Gene: ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10". 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.