ABCC10

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ABCC10
Identifiers
Aliases ABCC10, EST182763, MRP7, SIMRP7, ATP binding cassette subfamily C member 10
External IDs MGI: 2386976 HomoloGene: 58616 GeneCards: ABCC10
Gene location (Human)
Chromosome 6 (human)
Chr. Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for ABCC10
Genomic location for ABCC10
Band 6p21.1 Start 43,427,366 bp[1]
End 43,450,430 bp[1]
RNA expression pattern
PBB GE ABCC10 213485 s at fs.png

PBB GE ABCC10 215873 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001198934
NM_033450
NM_001350518

NM_145140
NM_170680
NM_001347396

RefSeq (protein)

NP_001185863
NP_258261
NP_001337447

NP_001334325
NP_660122
NP_733780

Location (UCSC) Chr 6: 43.43 – 43.45 Mb Chr 6: 46.3 – 46.33 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.[5][6]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124574 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032842 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum Mol Genet. 5 (10): 1649–55. PMID 8894702. doi:10.1093/hmg/5.10.1649. 
  6. ^ a b "Entrez Gene: ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.