ABCC10

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ABCC10
Identifiers
Aliases ABCC10, EST182763, MRP7, SIMRP7, ATP binding cassette subfamily C member 10
External IDs MGI: 2386976 HomoloGene: 58616 GeneCards: 89845
RNA expression pattern
PBB GE ABCC10 213485 s at tn.png

PBB GE ABCC10 215873 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001198934
NM_033450

NM_145140
NM_170680

RefSeq (protein)

NP_001185863.1
NP_258261.2

NP_660122.1
NP_733780.1

Location (UCSC) Chr 6: 43.43 – 43.45 Mb Chr 17: 46.3 – 46.33 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.[1][2]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.[2]

See also[edit]

References[edit]

  1. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum Mol Genet 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702. 
  2. ^ a b "Entrez Gene: ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.