ABLIM3

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ABLIM3
Protein ABLIM3 PDB 1ujs.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ABLIM3, HMFN1661, actin binding LIM protein family member 3
External IDs MGI: 2442582 HomoloGene: 69175 GeneCards: 22885
RNA expression pattern
PBB GE ABLIM3 205730 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301015
NM_001301018
NM_001301027
NM_001301028
NM_014945

NM_001164491
NM_198649

RefSeq (protein)

NP_001287944.1
NP_001287947.1
NP_001287956.1
NP_001287957.1
NP_055760.1

NP_001157963.1
NP_941051.2

Location (UCSC) Chr 5: 149.14 – 149.26 Mb Chr 18: 61.8 – 61.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Actin-binding LIM protein 3 is a protein that in humans is encoded by the ABLIM3 gene.[3]

Function[edit]

The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer.[4] An important paralog of this gene is LIMS1.

Clinical relevance[edit]

Diseases associated with ABLIM3 include hepatoblastoma, and among its related super-pathways are axon guidance and DCC mediated attractive signaling.

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: ABLIM3 actin binding LIM protein family, member 3". 
  4. ^ Krupp M, Weinmann A, Galle PR, Teufel A (Jan 2006). "Actin binding LIM protein 3 (abLIM3)". International Journal of Molecular Medicine. 17 (1): 129–33. doi:10.3892/ijmm.17.1.129. PMID 16328021. 

Further reading[edit]