ABRA (gene)

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Actin binding Rho activating protein
Symbols ABRA ; STARS
External IDs OMIM609747 MGI2444891 HomoloGene34713 GeneCards: ABRA Gene
RNA expression pattern
PBB GE ABRA gnf1h08948 at tn.png
More reference expression data
Species Human Mouse
Entrez 137735 223513
Ensembl ENSG00000174429 ENSMUSG00000042895
UniProt Q8N0Z2 Q8BUZ1
RefSeq (mRNA) NM_139166 NM_175456
RefSeq (protein) NP_631905 NP_780665
Location (UCSC) Chr 8:
106.76 – 106.77 Mb
Chr 15:
41.87 – 41.87 Mb
PubMed search [1] [2]

Actin-binding Rho-activating protein is a protein that in humans is encoded by the ABRA gene.[1] The mouse and rat homologues are known as STARS (striated muscle activator of Rho signalling) and MS1 (myocyte stress 1) respectively.[2]

MS1/STARS is regulated by MyoD during myogenic differentiation of the C2C12 cell line.


  1. ^ Arai A, Spencer JA, Olson EN (Jul 2002). "STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription". J Biol Chem 277 (27): 24453–9. doi:10.1074/jbc.M202216200. PMID 11983702. 
  2. ^ "Entrez Gene: ABRA actin-binding Rho activating protein". 

Further reading[edit]