ACER2

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
ACER2
Identifiers
Aliases ACER2, ALKCDase2, ASAH3L, alkaline ceramidase 2
External IDs MGI: 1920932 HomoloGene: 14986 GeneCards: ACER2
Gene location (Human)
Chromosome 9 (human)
Chr. Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for ACER2
Genomic location for ACER2
Band 9p22.1 Start 19,409,059 bp[1]
End 19,452,020 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001010887

NM_001290541
NM_001290543
NM_139306

RefSeq (protein)

NP_001010887

NP_001277470
NP_001277472
NP_647467

Location (UCSC) Chr 9: 19.41 – 19.45 Mb Chr 4: 86.87 – 86.93 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Alkaline ceramidase 2 also known as ACER2 is a ceramidase enzyme which in humans is encoded by the ACER2 gene.[5]

Function[edit]

The ACER2/sphingosine pathway plays an important role in regulating integrin β1 subunit (ITGB1) maturation and cell adhesion mediated by β1 integrins.[6]

References[edit]

External links[edit]

Further reading[edit]