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Acyl-CoA thioesterase 12
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ACOT12 ; CACH-1; Cach; STARD15; THEAL
External IDs OMIM614315 MGI1921406 HomoloGene12540 GeneCards: ACOT12 Gene
EC number
RNA expression pattern
PBB GE ACOT12 gnf1h08567 at tn.png
More reference expression data
Species Human Mouse
Entrez 134526 74156
Ensembl ENSG00000172497 ENSMUSG00000021620
UniProt Q8WYK0 Q9DBK0
RefSeq (mRNA) NM_130767 NM_028790
RefSeq (protein) NP_570123 NP_083066
Location (UCSC) Chr 5:
81.33 – 81.39 Mb
Chr 13:
91.74 – 91.79 Mb
PubMed search [1] [2]

Acyl-coenzyme A thioesterase 12 or StAR-related lipid transfer protein 15 (STARD15) is an enzyme that in humans is encoded by the ACOT12 gene.[1][2][3] The protein contains a StAR-related lipid transfer domain.


  1. ^ Hunt MC, Yamada J, Maltais LJ, Wright MW, Podesta EJ, Alexson SE (Aug 2005). "A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases". J Lipid Res 46 (9): 2029–32. doi:10.1194/jlr.E500003-JLR200. PMID 16103133. 
  2. ^ Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE (Aug 2006). "Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs". FASEB J 20 (11): 1855–64. doi:10.1096/fj.06-6042com. PMID 16940157. 
  3. ^ "Entrez Gene: ACOT12 acyl-CoA thioesterase 12". 

Further reading[edit]