ACP2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
ACP2
Identifiers
Aliases ACP2, acid phosphatase 2, lysosomal, LAP
External IDs MGI: 87882 HomoloGene: 1217 GeneCards: ACP2
RNA expression pattern
PBB GE ACP2 202767 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007387

RefSeq (protein)

NP_001289418
NP_001289419
NP_001289420
NP_001289421
NP_001601

NP_031413.1
NP_031413

Location (UCSC) Chr 11: 47.24 – 47.25 Mb Chr 2: 91.2 – 91.21 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene.[3][4]

Lysosomal acid phosphatase is composed of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Shows TB, Brown JA, Lalley PA (Dec 1976). "Assignment and linear order of human acid phosphatase-2, esterase A4, and lactate dehydrogenase A genes on chromosome 11". Cytogenet Cell Genet. 16 (1-5): 231–4. doi:10.1159/000130598. PMID 975882. 
  4. ^ a b "Entrez Gene: ACP2 acid phosphatase 2, lysosomal". 

External links[edit]

Further reading[edit]