ADAM28

From Wikipedia, the free encyclopedia
Jump to: navigation, search
ADAM28
Identifiers
Aliases ADAM28, ADAM 28, ADAM23, MDC-L, MDC-Lm, MDC-Ls, MDCL, eMDC II, eMDCII, ADAM metallopeptidase domain 28
External IDs MGI: 105988 HomoloGene: 40705 GeneCards: ADAM28
RNA expression pattern
PBB GE ADAM28 208269 s at fs.png

PBB GE ADAM28 205997 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001304351
NM_014265
NM_021777

NM_001048175
NM_010082
NM_176991
NM_183366

RefSeq (protein)

NP_001291280
NP_055080
NP_068547

Location (UCSC) Chr 8: 24.29 – 24.36 Mb Chr 14: 68.61 – 68.66 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene.[3]

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell–cell and cell–matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.[3]

References[edit]

Further reading[edit]

External links[edit]