ADH4

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ADH4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ADH4, ADH-2, HEL-S-4, alcohol dehydrogenase 4 (class II), pi polypeptide
External IDs MGI: 1349472 HomoloGene: 20162 GeneCards: ADH4
Gene location (Human)
Chromosome 4 (human)
Chr. Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for ADH4
Genomic location for ADH4
Band 4q23 Start 99,123,657 bp[1]
End 99,157,792 bp[1]
RNA expression pattern
PBB GE ADH4 gnf1h00032 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000670
NM_001306171
NM_001306172

NM_011996

RefSeq (protein)

NP_000661
NP_001293100
NP_001293101

NP_036126

Location (UCSC) Chr 4: 99.12 – 99.16 Mb Chr 4: 138.42 – 138.43 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene.[5]

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.[5]

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