AFAP1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
AFAP1
Identifiers
Aliases AFAP1, AFAP, AFAP-110, AFAP110, actin filament associated protein 1
External IDs MGI: 1917542 HomoloGene: 11009 GeneCards: AFAP1
RNA expression pattern
PBB GE AFAP1 203563 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001134647
NM_021638
NM_198595

NM_027373

RefSeq (protein)

NP_001128119
NP_940997

NP_081649.1
NP_081649

Location (UCSC) Chr 4: 7.76 – 7.94 Mb Chr 5: 35.89 – 36 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Actin filament-associated protein 1 is a protein that in humans is encoded by the AFAP1 gene.[3][4][5][6]

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Two alternative transcripts encoding the same protein have been identified.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Qian Y, Gatesman AS, Baisden JM, Zot HG, Cherezova L, Qazi I, Mazloum N, Lee MY, Guappone-Koay A, Flynn DC (Feb 2004). "Analysis of the role of the leucine zipper motif in regulating the ability of AFAP-110 to alter actin filament integrity". J Cell Biochem. 91 (3): 602–20. doi:10.1002/jcb.10725. PMID 14755689. 
  4. ^ Baisden JM, Gatesman AS, Cherezova L, Jiang BH, Flynn DC (Oct 2001). "The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases". Oncogene. 20 (45): 6607–16. doi:10.1038/sj.onc.1204802. PMID 11641786. 
  5. ^ Baisden JM, Qian Y, Zot HM, Flynn DC (Oct 2001). "The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity". Oncogene. 20 (44): 6435–47. doi:10.1038/sj.onc.1204784. PMID 11607843. 
  6. ^ a b "Entrez Gene: AFAP1 actin filament associated protein 1". 

External links[edit]

Further reading[edit]