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AH109 is a strain of yeast (Saccharomyces cerevisiae) used in biological research for two-hybrid screening. The strain is sold commercially by Clontech [1] and is used as a partner with strain Y187 in mating assays.[2]


  1. ^ DeFrancesco, Laura; Wilkinson, Deborah (Apr 12, 1999). "The Two Body Problem". The Scientist. 13 (8): 21. 
  2. ^ Guo, Deyin; Rajamäki, Minna-Liisa; Valkonen, Jari (2008). "Protein–Protein Interactions: The Yeast Two-Hybrid System". Methods in Molecular Biology. Plant Virology Protocols. 451 (3): 421–439. doi:10.1007/978-1-59745-102-4_29.