ALDH1A3

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ALDH1A3
Identifiers
Aliases ALDH1A3, ALDH1A6, ALDH6, MCOP8, RALDH3, aldehyde dehydrogenase 1 family member A3
External IDs MGI: 1861722 HomoloGene: 68080 GeneCards: ALDH1A3
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293815
NM_000693
NM_001037224

NM_053080

RefSeq (protein)

NP_000684
NP_001280744

NP_444310.3
NP_444310

Location (UCSC) Chr 15: 100.88 – 100.92 Mb Chr 7: 66.39 – 66.43 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene,[3]

Function[edit]

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Hsu LC, Chang WC, Hiraoka L, Hsieh CL (November 1994). "Molecular cloning, genomic organization, and chromosomal localization of an additional human aldehyde dehydrogenase gene, ALDH6". Genomics. 24 (2): 333–41. doi:10.1006/geno.1994.1624. PMID 7698756. 
  4. ^ "Entrez Gene: ALDH1A3". 

External links[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.