ALG3

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ALG3
Identifiers
Aliases ALG3, CDG1D, CDGS4, D16Ertd36e, NOT56L, Not56, CDGS6, not, alpha-1,3- mannosyltransferase
External IDs MGI: 1098592 HomoloGene: 4228 GeneCards: 10195
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001006940
NM_001006941
NM_005787

NM_145939

RefSeq (protein)

NP_001006942.1
NP_005778.1

NP_666051.2

Location (UCSC) Chr 3: 184.24 – 184.25 Mb Chr 16: 20.61 – 20.61 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase is an enzyme that in humans is encoded by the ALG3 gene.[3][4]

This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Jerrold LE (Dec 1975). "Will an electric current replace the syringe for anesthesia?". Dent Stud. 53 (5): 49, 54. PMID 1058125. 
  4. ^ a b "Entrez Gene: ALG3 asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)". 

Further reading[edit]

External links[edit]