ALG3

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
ALG3
Identifiers
AliasesALG3, CDG1D, CDGS4, D16Ertd36e, NOT56L, Not56, CDGS6, not, alpha-1,3- mannosyltransferase, ALG3 alpha-1,3- mannosyltransferase
External IDsMGI: 1098592 HomoloGene: 4228 GeneCards: ALG3
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for ALG3
Genomic location for ALG3
Band3q27.1Start184,242,301 bp[1]
End184,249,548 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001006940
NM_001006941
NM_005787

NM_145939
NM_001357403
NM_001357404
NM_001357405
NM_001357406

RefSeq (protein)

NP_001006942
NP_005778

NP_666051
NP_001344332
NP_001344333
NP_001344334
NP_001344335

Location (UCSC)Chr 3: 184.24 – 184.25 MbChr 16: 20.61 – 20.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase is an enzyme that, in humans, is encoded by the ALG3 gene.[5][6]

This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000214160 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033809 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Jerrold LE (Dec 1975). "Will an electric current replace the syringe for anesthesia?". Dent Stud. 53 (5): 49, 54. PMID 1058125.
  6. ^ a b "Entrez Gene: ALG3 asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)".

Further reading[edit]

External links[edit]