ALG8

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ALG8
Identifiers
Aliases ALG8, CDG1H, alpha-1,3-glucosyltransferase
External IDs MGI: 2141959 HomoloGene: 6931 GeneCards: ALG8
RNA expression pattern
PBB GE ALG8 203545 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001007027
NM_001007028
NM_024079

NM_199035

RefSeq (protein)

NP_001007028
NP_076984

NP_950200.2
NP_950200

Location (UCSC) Chr 11: 78.1 – 78.14 Mb Chr 7: 97.37 – 97.39 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase is an enzyme that in humans is encoded by the ALG8 gene.[3]

This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.[3]

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