AMY2B

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AMY2B
Protein AMY2B PDB 1b2y.png
Identifiers
AliasesAMY2B, AMY2, AMY3, HXA, amylase, alpha 2B (pancreatic), amylase alpha 2B (pancreatic), amylase alpha 2B
External IDsOMIM: 104660 MGI: 3714985 HomoloGene: 134663 GeneCards: AMY2B
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for AMY2B
Genomic location for AMY2B
Band1p21.1Start103,553,815 bp[1]
End103,579,534 bp[1]
RNA expression pattern
PBB GE AMY2B 208498 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020978

NM_001160151

RefSeq (protein)

NP_066188

NP_001153622

Location (UCSC)Chr 1: 103.55 – 103.58 MbChr 3: 113.31 – 113.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene.[5][6]

Function[edit]

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside] bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000240038 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000093931 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Omichi K, Hase S (December 1993). "Identification of the characteristic amino-acid sequence for human alpha-amylase encoded by the AMY2B gene". Biochimica et Biophysica Acta. 1203 (2): 224–9. doi:10.1016/0167-4838(93)90087-8. PMID 8268204.
  6. ^ a b "Entrez Gene: AMY2B amylase, alpha 2B (pancreatic)".

External links[edit]

Further reading[edit]