ANKRD15

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KANK1
Identifiers
Aliases KANK1, ANKRD15, CPSQ2, KANK, KN motif and ankyrin repeat domains 1
External IDs MGI: 2147707 HomoloGene: 17706 GeneCards: 23189
RNA expression pattern
PBB GE ANKRD15 213005 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256876
NM_001256877
NM_015158
NM_153186

NM_181404

RefSeq (protein)

NP_001243805.1
NP_001243806.1
NP_055973.2

n/a

Location (UCSC) Chr 9: 0.47 – 0.75 Mb Chr 19: 25.24 – 25.43 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

KN motif and ankyrin repeat domain-containing protein 1 is a protein that in humans is encoded by the KANK1 gene.[1][2][3]

This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified.[3]

References[edit]

  1. ^ Sarkar S, Roy BC, Hatano N, Aoyagi T, Gohji K, Kiyama R (Sep 2002). "A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma". J Biol Chem 277 (39): 36585–91. doi:10.1074/jbc.M204244200. PMID 12133830. 
  2. ^ Zhu Y, Kakinuma N, Wang Y, Kiyama R (Jan 2008). "Kank proteins: a new family of ankyrin-repeat domain-containing proteins". Biochim Biophys Acta 1780 (2): 128–33. doi:10.1016/j.bbagen.2007.09.017. PMID 17996375. 
  3. ^ a b "Entrez Gene: ANKRD15 ankyrin repeat domain 15". 

Further reading[edit]