AP2A2

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AP2A2
Protein AP2A2 PDB 1b9k.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit
External IDs MGI: 101920 HomoloGene: 5335 GeneCards: 161
Genetically Related Diseases
Disease Name References
Alzheimer's disease
RNA expression pattern
PBB GE AP2A2 211779 x at tn.png

PBB GE AP2A2 212159 x at tn.png

PBB GE AP2A2 212161 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001242837
NM_012305

NM_007459

RefSeq (protein)

NP_001229766.1
NP_036437.1

NP_031485.3

Location (UCSC) Chr 11: 0.92 – 1.01 Mb Chr 7: 141.56 – 141.63 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.[1][2][3]

Interactions[edit]

AP2A2 has been shown to interact with EPN1[4] and SHC1.[5]

References[edit]

  1. ^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202. 
  2. ^ Robinson MS (Mar 1989). "Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins)". The Journal of Cell Biology 108 (3): 833–42. doi:10.1083/jcb.108.3.833. PMC 2115374. PMID 2564002. 
  3. ^ "Entrez Gene: AP2A2 adaptor-related protein complex 2, alpha 2 subunit". 
  4. ^ Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (Aug 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis". Nature 394 (6695): 793–7. doi:10.1038/29555. PMID 9723620. 
  5. ^ Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M (Mar 1996). "Interaction of Shc with adaptor protein adaptins". The Journal of Biological Chemistry 271 (9): 5265–9. doi:10.1074/jbc.271.9.5265. PMID 8617812. 

Further reading[edit]