AP3D1

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AP3D1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AP3D1, ADTD, hBLVR, adaptor related protein complex 3 delta 1 subunit
External IDs MGI: 107734 HomoloGene: 2926 GeneCards: 8943
RNA expression pattern
PBB GE AP3D1 206592 s at tn.png

PBB GE AP3D1 208710 s at tn.png

PBB GE AP3D1 210974 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001077523
NM_001261826
NM_003938

NM_007460

RefSeq (protein)

NP_001248755.1
NP_003929.4

NP_031486.1

Location (UCSC) Chr 19: 2.1 – 2.16 Mb Chr 10: 80.71 – 80.74 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene.[1][2][3]

Function[edit]

AP3D1 is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.[supplied by OMIM][3]

Interactions[edit]

AP3D1 has been shown to interact with SYBL1.[4]

References[edit]

  1. ^ Simpson F, Peden AA, Christopoulou L, Robinson MS (May 1997). "Characterization of the adaptor-related protein complex, AP-3". The Journal of Cell Biology 137 (4): 835–45. doi:10.1083/jcb.137.4.835. PMC 2139840. PMID 9151686. 
  2. ^ Ooi CE, Moreira JE, Dell'Angelica EC, Poy G, Wassarman DA, Bonifacino JS (Aug 1997). "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet". The EMBO Journal 16 (15): 4508–18. doi:10.1093/emboj/16.15.4508. PMC 1170077. PMID 9303295. 
  3. ^ a b "Entrez Gene: AP3D1 adaptor-related protein complex 3, delta 1 subunit". 
  4. ^ Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V, Daviet L, Formstecher E, Hamburger A, Filippini F, D'Esposito M, Galli T (Jul 2003). "A dual mechanism controlling the localization and function of exocytic v-SNAREs". Proceedings of the National Academy of Sciences of the United States of America 100 (15): 9011–6. doi:10.1073/pnas.1431910100. PMC 166429. PMID 12853575. 

Further reading[edit]