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Available structures
PDB Ortholog search: PDBe RCSB
Aliases AP3D1, ADTD, hBLVR, adaptor related protein complex 3 delta 1 subunit, HPS10, adaptor related protein complex 3 subunit delta 1
External IDs MGI: 107734 HomoloGene: 2926 GeneCards: AP3D1
Gene location (Human)
Chromosome 19 (human)
Chr. Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for AP3D1
Genomic location for AP3D1
Band 19p13.3 Start 2,100,988 bp[1]
End 2,164,468 bp[1]
RNA expression pattern
PBB GE AP3D1 208710 s at fs.png

PBB GE AP3D1 210974 s at fs.png

PBB GE AP3D1 206592 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 19: 2.1 – 2.16 Mb Chr 10: 80.71 – 80.74 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene.[5][6][7]


AP3D1 is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.[supplied by OMIM][7]


AP3D1 has been shown to interact with SYBL1.[8]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000065000 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020198 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Simpson F, Peden AA, Christopoulou L, Robinson MS (May 1997). "Characterization of the adaptor-related protein complex, AP-3". The Journal of Cell Biology. 137 (4): 835–45. doi:10.1083/jcb.137.4.835. PMC 2139840Freely accessible. PMID 9151686. 
  6. ^ Ooi CE, Moreira JE, Dell'Angelica EC, Poy G, Wassarman DA, Bonifacino JS (Aug 1997). "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet". The EMBO Journal. 16 (15): 4508–18. doi:10.1093/emboj/16.15.4508. PMC 1170077Freely accessible. PMID 9303295. 
  7. ^ a b "Entrez Gene: AP3D1 adaptor-related protein complex 3, delta 1 subunit". 
  8. ^ Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V, Daviet L, Formstecher E, Hamburger A, Filippini F, D'Esposito M, Galli T (Jul 2003). "A dual mechanism controlling the localization and function of exocytic v-SNAREs". Proceedings of the National Academy of Sciences of the United States of America. 100 (15): 9011–6. doi:10.1073/pnas.1431910100. PMC 166429Freely accessible. PMID 12853575. 

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